The flight distance from Cairo International Airport (CAI) in Cairo, Egypt to Sao Tome International Airport (TMS) in Sao Tome, São Tomé and Príncipe is 4,214 kilometers (2,618 miles / 2,275 nautical miles). The estimated flight time for this route is approximately 6h, flying southwest at a heading of 223°.

This is a long-haul route typically operated by wide-body aircraft such as the Boeing 777 or Airbus A350. Full meal service, in-flight entertainment, and comfort amenities are standard.

This is an international route connecting Egypt with São Tomé and Príncipe. Travelers should check visa requirements, customs regulations, and any travel advisories before booking.

Time zone information: When it's 01:55 in Cairo, it's 23:55 in Sao Tome.

The return flight from Sao Tome (TMS) to Cairo (CAI) follows a heading of 36° (northeast). Actual flight times may vary depending on wind conditions, air traffic, and the specific aircraft used.

For more information about these airports, visit the Cairo International Airport (CAI) and Sao Tome International Airport (TMS) detail pages, or use our flight duration calculator to compare other routes.