The flight distance from Vilo Acuna International Airport (CYO) in Cayo Largo del Sur, Cuba to Guarulhos - Governador Andre Franco Montoro International Airport (GRU) in Sao Paulo, Brazil is 6,286 kilometers (3,906 miles / 3,394 nautical miles). The estimated flight time for this route is approximately 8h, flying southeast at a heading of 141°.

This is a long-haul route typically operated by wide-body aircraft such as the Boeing 777 or Airbus A350. Full meal service, in-flight entertainment, and comfort amenities are standard.

This is an international route connecting Cuba with Brazil. It is an intercontinental flight between North America and South America. Travelers should check visa requirements, customs regulations, and any travel advisories before booking.

Time zone information: When it's 12:45 in Cayo Largo del Sur, it's 14:45 in Sao Paulo.

There is a significant elevation difference of 2,449 feet between the two airports. Guarulhos - Governador Andre Franco Montoro International Airport sits higher than Vilo Acuna International Airport.

The return flight from Sao Paulo (GRU) to Cayo Largo del Sur (CYO) follows a heading of 320° (northwest). Actual flight times may vary depending on wind conditions, air traffic, and the specific aircraft used.

For more information about these airports, visit the Vilo Acuna International Airport (CYO) and Guarulhos - Governador Andre Franco Montoro International Airport (GRU) detail pages, or use our flight duration calculator to compare other routes.