The flight distance from Denver International Airport (DEN) in Denver, United States to St. Mary's Airport (ISC) in St. Mary's, United Kingdom is 7,258 kilometers (4,510 miles / 3,919 nautical miles). The estimated flight time for this route is approximately 10h, flying northeast at a heading of 45°.

This is a long-haul route typically operated by wide-body aircraft such as the Boeing 777 or Airbus A350. Full meal service, in-flight entertainment, and comfort amenities are standard.

This is an international route connecting United States with United Kingdom. It is an intercontinental flight between North America and Europe. Travelers should check visa requirements, customs regulations, and any travel advisories before booking.

Time zone information: When it's 04:52 in Denver, it's 11:52 in St. Mary's. With a 7-hour time difference, travelers should plan for significant jet lag. It typically takes one day per hour of time difference to fully adjust.

There is a significant elevation difference of 5,318 feet between the two airports. St. Mary's Airport sits lower than Denver International Airport. Travelers arriving at the higher-elevation airport should be aware of potential altitude effects.

The return flight from St. Mary's (ISC) to Denver (DEN) follows a heading of 303° (west northwest). Actual flight times may vary depending on wind conditions, air traffic, and the specific aircraft used.

For more information about these airports, visit the Denver International Airport (DEN) and St. Mary's Airport (ISC) detail pages, or use our flight duration calculator to compare other routes.