The flight distance from Key West International Airport (EYW) in Key West, United States to San Diego International Airport (SAN) in San Diego, United States is 3,557 kilometers (2,210 miles / 1,921 nautical miles). The estimated flight time for this route is approximately 5h, flying west northwest at a heading of 293°.

This is a medium-haul route that may be operated by either narrow-body or wide-body aircraft depending on demand. Passengers can expect a meal service on most carriers.

This is a domestic route within United States. Both airports operate in the same country, which may simplify travel requirements and documentation. Despite being a domestic route, there is a 3-hour time difference between the two cities.

Time zone information: When it's 05:35 in Key West, it's 02:35 in San Diego. The 3-hour time difference may cause some jet lag. Most travelers adjust within a day or two.

The return flight from San Diego (SAN) to Key West (EYW) follows a heading of 96° (east). Actual flight times may vary depending on wind conditions, air traffic, and the specific aircraft used.

For more information about these airports, visit the Key West International Airport (EYW) and San Diego International Airport (SAN) detail pages, or use our flight duration calculator to compare other routes.