The flight distance from Harry Reid International Airport (LAS) in Las Vegas, United States to Ruben Cantu Airport (SYP) in Santiago, Panama is 4,656 kilometers (2,893 miles / 2,514 nautical miles). The estimated flight time for this route is approximately 6h, flying east southeast at a heading of 124°.

This is a long-haul route typically operated by wide-body aircraft such as the Boeing 777 or Airbus A350. Full meal service, in-flight entertainment, and comfort amenities are standard.

This is an international route connecting United States with Panama. Travelers should check visa requirements, customs regulations, and any travel advisories before booking.

Time zone information: When it's 05:10 in Las Vegas, it's 08:10 in Santiago. The 3-hour time difference may cause some jet lag. Most travelers adjust within a day or two.

There is a significant elevation difference of 1,909 feet between the two airports. Ruben Cantu Airport sits lower than Harry Reid International Airport.

The return flight from Santiago (SYP) to Las Vegas (LAS) follows a heading of 317° (northwest). Actual flight times may vary depending on wind conditions, air traffic, and the specific aircraft used.

For more information about these airports, visit the Harry Reid International Airport (LAS) and Ruben Cantu Airport (SYP) detail pages, or use our flight duration calculator to compare other routes.