The flight distance from Lisbon Portela Airport (LIS) in Lisbon, Portugal to Ruben Cantu Airport (SYP) in Santiago, Panama is 7,871 kilometers (4,891 miles / 4,250 nautical miles). The estimated flight time for this route is approximately 10h, flying west at a heading of 265°.

This is a long-haul route typically operated by wide-body aircraft such as the Boeing 777 or Airbus A350. Full meal service, in-flight entertainment, and comfort amenities are standard.

This is an international route connecting Portugal with Panama. It is an intercontinental flight between Europe and North America. Travelers should check visa requirements, customs regulations, and any travel advisories before booking.

Time zone information: When it's 15:43 in Lisbon, it's 10:43 in Santiago. The 5-hour time difference may cause some jet lag. Most travelers adjust within a day or two.

The return flight from Santiago (SYP) to Lisbon (LIS) follows a heading of 52° (northeast). Actual flight times may vary depending on wind conditions, air traffic, and the specific aircraft used.

For more information about these airports, visit the Lisbon Portela Airport (LIS) and Ruben Cantu Airport (SYP) detail pages, or use our flight duration calculator to compare other routes.