The flight distance from Licenciado Benito Juarez International Airport (MEX) in Mexico City, Mexico to Ruben Cantu Airport (SYP) in Santiago, Panama is 2,325 kilometers (1,445 miles / 1,255 nautical miles). The estimated flight time for this route is approximately 4h, flying east southeast at a heading of 120°.

This is a medium-haul route that may be operated by either narrow-body or wide-body aircraft depending on demand. Passengers can expect a meal service on most carriers.

This is an international route connecting Mexico with Panama. Travelers should check visa requirements, customs regulations, and any travel advisories before booking.

Time zone information: When it's 11:45 in Mexico City, it's 12:45 in Santiago.

There is a significant elevation difference of 7,044 feet between the two airports. Ruben Cantu Airport sits lower than Licenciado Benito Juarez International Airport. Travelers arriving at the higher-elevation airport should be aware of potential altitude effects.

The return flight from Santiago (SYP) to Mexico City (MEX) follows a heading of 305° (northwest). Actual flight times may vary depending on wind conditions, air traffic, and the specific aircraft used.

For more information about these airports, visit the Licenciado Benito Juarez International Airport (MEX) and Ruben Cantu Airport (SYP) detail pages, or use our flight duration calculator to compare other routes.