The flight distance from Enrique Adolfo Jimenez Airport (ONX) in Colon, Panama to San Diego International Airport (SAN) in San Diego, United States is 4,624 kilometers (2,873 miles / 2,497 nautical miles). The estimated flight time for this route is approximately 6h, flying northwest at a heading of 310°.

This is a long-haul route typically operated by wide-body aircraft such as the Boeing 777 or Airbus A350. Full meal service, in-flight entertainment, and comfort amenities are standard.

This is an international route connecting Panama with United States. Travelers should check visa requirements, customs regulations, and any travel advisories before booking.

Time zone information: When it's 08:27 in Colon, it's 05:27 in San Diego. The 3-hour time difference may cause some jet lag. Most travelers adjust within a day or two.

The return flight from San Diego (SAN) to Colon (ONX) follows a heading of 116° (east southeast). Actual flight times may vary depending on wind conditions, air traffic, and the specific aircraft used.

For more information about these airports, visit the Enrique Adolfo Jimenez Airport (ONX) and San Diego International Airport (SAN) detail pages, or use our flight duration calculator to compare other routes.