The flight distance from Phoenix Sky Harbor International Airport (PHX) in Phoenix, United States to Ruben Cantu Airport (SYP) in Santiago, Panama is 4,253 kilometers (2,643 miles / 2,297 nautical miles). The estimated flight time for this route is approximately 6h, flying southeast at a heading of 124°.

This is a long-haul route typically operated by wide-body aircraft such as the Boeing 777 or Airbus A350. Full meal service, in-flight entertainment, and comfort amenities are standard.

This is an international route connecting United States with Panama. Travelers should check visa requirements, customs regulations, and any travel advisories before booking.

Time zone information: When it's 07:46 in Phoenix, it's 09:46 in Santiago.

The return flight from Santiago (SYP) to Phoenix (PHX) follows a heading of 316° (northwest). Actual flight times may vary depending on wind conditions, air traffic, and the specific aircraft used.

For more information about these airports, visit the Phoenix Sky Harbor International Airport (PHX) and Ruben Cantu Airport (SYP) detail pages, or use our flight duration calculator to compare other routes.