The flight distance from Ninoy Aquino International Airport (MNL) in Manila, Philippines to Ruben Cantu Airport (SYP) in Santiago, Panama is 16,524 kilometers (10,268 miles / 8,922 nautical miles). The estimated flight time for this route is approximately 20h, flying northeast at a heading of 45°.

This is an ultra-long-haul route, one of the longest in aviation. It requires wide-body aircraft with extended range capability such as the Airbus A350-900ULR or Boeing 777-200LR. Passengers should prepare for an extended flight with multiple meal services.

This is an international route connecting Philippines with Panama. It is an intercontinental flight between Asia and North America. Travelers should check visa requirements, customs regulations, and any travel advisories before booking.

Time zone information: When it's 22:02 in Manila, it's 09:02 in Santiago. With a 13-hour time difference, travelers should plan for significant jet lag. It typically takes one day per hour of time difference to fully adjust.

The return flight from Santiago (SYP) to Manila (MNL) follows a heading of 316° (northwest). Actual flight times may vary depending on wind conditions, air traffic, and the specific aircraft used.

For more information about these airports, visit the Ninoy Aquino International Airport (MNL) and Ruben Cantu Airport (SYP) detail pages, or use our flight duration calculator to compare other routes.